Week 13 in the NFL features a fantastic headliner on Monday Night Football along with several pivotal matchups in both the NFC and AFC playoff races. This article will cover the Patriots at Bills, Ravens at Steelers, Chargers at Bengals, and 49ers at Seahawks, while Part Two of The Professor's NFL Games of the Week will cover the Football Team at the Raiders, the Broncos at the Chiefs, the Eagles at the Jets, and the Vikings at the Lions. All spreads and totals are provided by DraftKings.

New England Patriots at Buffalo Bills (BUF -3, Total 43.5)

The NFL's Monday Night Football game should be the first of many matchups between Bills quarterback Josh Allen and Patriots quarterback Mac Jones, who both have their teams in the thick of the crowded AFC playoff race. The two quarterbacks are about as different as two players can be from a skillset perspective, but both coaching staffs have found a formula that has allowed them to be reasonably successful around their signal-caller during this NFL season.

A critical question for Buffalo entering the game is how they will deal with New England's physical style; this is particularly true for the Bills offense, where coordinator Brian Daboll prefers to spread things out in 10 or 11 personnel to get his playmakers the ball in space. When Allen is clicking with his receivers, this offense has as high a ceiling as any, but the Bills seem to lack a "Plan B" when their first option sputters.